PHAR 520 Pharmacokinetics & Pharmacodynamics

This course introduces students to the principal factors that can impact absorption, distribution, and elimination of drugs in the body. Specifically, mathematical approaches to characterizing pharmacokinetics (PK), the study of factors influencing drug concentrations in the body, and pharmacodynamics (PD), the study of the physiologic action of drugs in the body, will be discussed with an emphasis on small molecule and protein therapeutics. The clinical and non-clinical applications of PK and PD will be discussed. Students will participate in simulations of real-world pharmacokinetic monitoring of various drugs used clinically to treat infections, control seizures, and suppress arrythmias.